Posted by Hemodialysis is a process where our blood is cleaned using a dialysis machine and a specific filter called a dialyzer. To get our blood into the dialyzer, the doctor needs to make an access, or entrance, into our blood vessels. Minor surgery is used to accomplish this, typically on our arms. The size of the Global Hemodialysis Market in 2021 was USD 85.49 million. By 2030, it is anticipated to reach an amount of USD 130.36 million, indicating a promising CAGR of 5.1 percent from the forecasted period of 2021 to 2030.
How does the dialysis machine purify the blood?
The dialyzer, or filter, is divided into two parts: one for your blood and one for a cleansing solution known as dialysate. These two components are separated by a thin membrane. Because blood cells, protein, and other vital substances are too large to travel through the barrier, they remain in your blood. Smaller waste items in the blood, such as urea, creatinine, potassium, and surplus fluid, are carried away by the membrane. Some of the most recent advancements in the Hemodialysis Market have been elucidated as follows:
List of top 4 advancements of Hemodialysis in the Healthcare Industry
a.) Adequacy of the Hemodialysis process
The adequacy level of HD is usually measured & assessed by Kt/V. This adequately represents the (K) or product of clearance per time multiplied by the total duration time (t) & adjusted for the body size by dividing this level of clearance by (V) or the distribution volume. Kt/V reflects the level of clearance of urea as a surrogate marker for clearance of small, but not large or mid-sized, uremic toxins.
The single-pool Kt/V often overestimates the efficiency of the delivered dose of dialysis, as it fails to account for the process of blood urea rebound after undergoing the process of dialysis. The equilibrated Kt/V, which corrects for urea rebound and is typically 0.15 to 0.20 lower than the single-pool Kt/V, provides a more precise measurement of the dialysis dose. Single-pool Kt/V should ideally be above 1.4 because lower values have been linked to higher morbidity, higher expenses, and shorter survival rates.
b.) Efficiency of the Hemodialysis process
The rate of arterial blood flow from healthy and functional vascular access is a key factor in HD effectiveness. Patients with end-stage renal disease who get regular Hemodialysis depend on their vascular access for survival. Arterio-venous fistula (AVF), arterio-venous graft (AVG), and central venous catheter are the three main kinds of vascular access (CVC). The patient’s outcome is directly correlated with the type of vascular access used.
c.) Compatibility of Hemodialysis process
Historically, the main component of dialysis membranes was cellulose (derived from cotton linter). The exposed hydroxyl groups on the surface of such membranes made them less biocompatible since they would stimulate complement to activate in blood passing past the membrane. Polymers like polyarylethersulfone, polyamide, polyvinylpyrrolidone, polycarbonate, and polyacrylonitrile have been used more recently to create membranes from synthetic materials. Comparatively to cellulose membranes that haven’t been substituted, these synthetic membranes lessen complement activation. The majority of synthetic membranes are high-flux. However, they can also be manufactured in low-flux configurations. Some of the most recent high-flux membranes use nanotechnology to produce uniform pore sizes.
d.) The Process of High Flux Hemodialysis
The ability of compact cartridges (high-flux dialyzers) to remove tiny solutes and “middle molecules” was improved by the development of bigger pore size semipermeable membranes with variable pore diameters. Compared to low-flux membranes, high-flux dialyzers allow the passage and removal of trapped solutes with higher molecular weights. If a dialyzer’s ultrafiltration coefficient (KUF) is greater than 15 ml/h/mmHg and its capacity to remove 2-M is greater than 20 ml/min, it is categorized as a high-flux type (a low-flux dialyzer removes KUF less than 15 ml/h/mmHg and 2-M less than 10 ml/min). To prevent reverse filtration of endotoxins and blood contamination, the fluids (dialysate and water) utilized with these high-flux dialyzers should be sterile, non-pyrogenic, and endotoxin-free.
CONCLUSION
The above-mentioned advancements in the field of Hemodialysis are expected to provide ample opportunities for growth in the future. Moreover, it is also expected to change the market outlook entirely in the future. Further, governments from all across the globe are emphasizing the Hemodialysis market due to the continuous rising in several blood diseases. Hence, they are planning to invest a hefty amount of money in technologically advanced surgeries to fulfill the demand of the patients in the future. It is expected by the experts that the advent of these highly developed surgical technologies will highly increase the demand of the market across the entire world which perfectly aligns with the above-mentioned statements.